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电影讲述大赵王朝四十年，西方蛮族兽主降世风云再起，镇魔司小队平异象行天命，勇征西域诛杀妖邪的故事，展现了镇魔司小队为保卫家国视死如归、荡气回肠的热血成长历程。

The biggest tech revolution of the 21st Century isn't digital, it's biological. A breakthrough called CRISPR has given us unprecedented control over the basic building blocks of life. It opens the door to curing diseases, reshaping the biosphere, and designing our own children. Human Nature is a provocative exploration of CRISPR's far-reaching implications, through the eyes of the scientists who discovered it, the families it's affecting, and the bioengineers who are testing its limits. How will this new power change our relationship with nature? What will it mean for human evolution? To begin to answer these questions we must look back billions of years and peer into an uncertain future.

外面拆迁的轰鸣声不断，那些欢笑和美好不断地萦绕在耳边，一个从未出过家门的盲女，就在这一天里，经历了无数的变化，在即将踏出家门的那一刻，她犹豫了……

本片根据真实人物改编。第一次来到西藏工作的老孔（宋洋 饰），急需一个翻译，机缘巧合下，找到了在内地读过书的久美（金巴 饰）。两个人从互相矛盾到彼此理解，最终成为了一生的朋友……