盖茨家族是出名的冒险家家族。本（尼古拉斯?凯奇 Nicolas Cage 饰）小时候就获悉了他们家族的一个惊天秘密：美国开国时埋藏国家财富的地点就藏在《独立宣言》中。尽管父亲不想盖茨家族在纠缠于国家宝藏，但本还是与电脑高手雷利（贾斯汀?巴萨 Justin Bartha 饰）一起开始了寻宝行动。本的寻宝计划很快陷入了僵局。与此同时，英国富豪伊恩（肖恩?宾 Sean Bean 饰）也盯上了这个宝藏，他派人潜入了美国国家图书找寻《独立宣言》中宝藏的秘密并密谋对付本。图书馆的艾比嘉尔博士（戴安?克鲁格 Diane Kruger 饰）获悉了伊恩的险恶用心后，决心帮助本找到国家宝藏……

这三位挚友老来得子，不得不与幼儿园校长、身为千禧一代的首席执行官，以及 1987年之后出现的所有事物对抗。

A satirical comedy about a down on his luck publicist, who gets his lucky break when he discovers a man recently released from a mental health facility looks just like a method actor who refuses to leave his trailer. With the help of a powerful producer, the publicist helps the man become a huge star, even marrying his beautiful leading lady. Their adventures lead them to cross paths with drunken costars, irreverent unhoused action heroes, unpredictable directors, super agent, and power-mad moguls. Fame and fortune are not all they're cracked up to be, and the two men must fight their way back to the things that matter the most.

一封寄给吴邪已故爷爷吴老狗的神秘来信，打乱了吴邪、张起灵、王胖子的退休计划。信件指向外蒙古的一个“彗星”墓，铁三角决定一探究竟，却意外卷入一场超乎想象的冒险。心怀叵测的蒙古悍匪、“彗星”的逃生倒计时、诡异的墓室规则，还有那个看不见的“它”，铁三角不得不放手一搏……