响（广濑铃 饰）答应帮助好友千草递情书给关矢老师（中村伦也 饰），哪知道在误打误撞之中将情书放在了伊藤老师（生田斗真 饰）的鞋柜里。伊藤老师是学校里出了名的冷面杀手，平日里看起来毫无感情，但响却在偶然之中发现了他热情善良的一面。实际上，伊藤也曾有过一段刻骨铭心的爱恋，但这段恋情结束的过于惨烈，让他对爱情彻底失去了信心。响渐渐喜欢上了伊藤老师，她用自己的温柔和天真融化了伊藤老师内心里的坚冰，两人终于互诉衷肠开始了交往。然而，伊藤老师冷冰冰的态度还是让响常常处于不安之中，不仅如此，伊藤老师曾经的恋人美崎来到了响所在的学校成为了实习老师。

佩恩（泰德·巴勃考克 Todd Babcock 饰）是生活在上海租界里的一名美国医生，一次偶尔的机会，他认识了国民党特务皓明（陶泽如 饰）。皓明年轻时受十月革命的感召也曾有过伟大的红色理想，但白色恐怖的残酷却让他改变初衷，拿起了屠杀共产党的屠刀。皓明的妻子自杀前把女儿秋秋送进了教会学校，秋秋（梅婷 饰）长大后在共产党人靳（张国荣 饰）的影响下加入共产党并且与靳假扮夫妻隐匿在上海为身患重病的靳治病。秋秋出现在佩恩面前时，佩恩对这个美丽的中国女人一见钟情。然而当他得知秋秋和靳的故事之后，在决定不顾一切的帮助他们的同时，还见证了那段浪漫又凄美的红色之恋。

In court for murder, Professor Moriarty is released seconds before Holmes arrives, too late, with vital evidence. Free again Moriarty vows to Holmes that his next crime will be so fiendish and amazing that Holmes's reputation will be finished. Moriarty sets about a fiendish plot involving the crown jewels and a series of mysteries to distract Holmes's mind.I enjoy most of this series as they all seem to run to the same formula. Here the plot goes back to basics and adds more of the mystery and less of the comedy. The plot is an enjoyable battle of wits between the two great minds. The downside is that the side-mystery that Moriarty sets up takes up the majority of the time and the two don't cross swords as well as they do in a gentlemanly beginning. The mystery surrounding Miss Brandon works OK but not really great as you know the whole time who is behind it and why. The jump to the crown jewels is too easily made and is a bit of a letdown.The comedy is less evident than usual but is still there. However it is overwhelmed by the more serious side. Bruce still does well but I was glad that he stood up to Holmes more than usual – telling him off for treating him like a child and such like. Rathbone is a good Holmes but his logic was off here and I wasn't as impressed by him as I usually am. Zucco is an interesting foil, but doesn't get enough time to work here. Lupino in an early role is interesting but a little too heavy and tads to overplay her tension a bit.Overall this is an OK addition to the series. The plot is reasonable but focuses too much on the diversion than the central characters and the reduction in comedy makes it feel a lot heavier than usual.

20世纪90年代末，中国香港。在一条平凡无奇的街道，楼间距极其逼仄的空间内充斥着形色各异的招牌。清晨时分，衣着考究的中年人（曹小卉 配音）一边打着手机一边坐进停靠在路边的出租车。他絮絮叨叨在嘱咐着名叫南茜的女孩，啰嗦之外自有一股浓郁的化不开的关怀。略显富态的司机发动汽车，可是却迷迷糊糊，东闯西撞，令后座的中年人很不耐烦。楼上，在家待业的女孩南茜（谷睿 配音）穿着随便地趴在床上，应付着老爹的碎碎念。曾经亲密的父女，似乎随着年岁的增长而渐行渐远。这时，敲门声响起，鬼马精灵调皮可爱的小女孩小美（黄婷婷 配音）捧着一筐鲜花站在门前。烦躁的南茜想尽快将她赶走，可听说今天是父亲节时，她的心中似有所动……本片荣获北京电影学院动画学院学院奖最佳导演奖。